Huperzine dose and timing?

I am going to give galantamine a rest and am wondering about dose and timing for huperzine. Any advice?


Hey @Richard, eager to hear how this goes for you. What made you decide to pause Galantamine?


I can’t speak for Richard, but I’ve had nothing but bad experiences with Galantamine. Generally I end up irritable, buzzing, and unable to fall back asleep for hours, and feel weird the next morning. Actually, writing this out, perhaps my dosage has always been too high…

I remember Charlie Morley also writes in Dreams of Awakening about how he tried galantamine once, had a dream that implied it was sacrilegious in some way, and never took it again.


What’s the story with huperzine? I haven’t see this mentioned with other supplements such as Gaba, Galantamine and 5-HTP. So how is this supposed to be used, supposed to work?


I got curious and did some searching. (Aside: Hey @kristenlamarca, do you know anything about this topic?)

Galantamine and Huperzine A are apparently both acetylcholinesterase inhibitors, so they would both increase levels of acetylcholine, which would boost REM/dreaming. At first glance there doesn’t seem to be as much research or detailed information on the use of Huperzine A for lucid dreaming compared to galantamine, but it’s definitely being used for that purpose and it seems like they would have similar effects on dreaming.

The discussion Alternating Galantamine and Huperzine-A? in another lucid dreaming forum talks about switching-off between the two as a means of avoiding becoming too resistant to the effects of one of them (personally I don’t generally think it’s a good idea to overuse anything like this, but to each her own). One post mentions dosage:

I have been using Galantamine and Huperzine A for a few years now and they made all the difference in the world. I went from having lucid dreams that were less than 5 minutes long to having 20 to 40 minutes long dreams. I also combine them with 600mg of Alpha GPC that really helps prolonging the dreams (This often produces dream chaining where I am kicked out of one lucid dream, only to enter another immediately after). Galantamine is difficult to get in Canada, which is why I started to use Huperzine A, which is also less expensive. I found that 400 mcg of Huperzine A does the same for me as 8 mg of Galantamine. I only use them on the weekend as to not create any resistance.

(That post also brings up two additional motivations: easier to get for some people, less expensive.)

I also did a quick search on academic articles in my college library database, but did not find any scholarly articles on using Huperzine A for lucid dreaming; in comparison I found 4 articles on galantamine and lucid dreaming. It would be interesting if someone did a study comparing the two (and placebo) and see what similarities and differences there are on dreaming/lucid dreaming.