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L-theanine
D-theanine.

" Overview

Theanine is an amino acid found in tea and some mushrooms. It comes in two forms: L-theanine and D-theanine. L-theanine is the most common form.

Theanine is similar to glutamate, a naturally occurring amino acid. Glutamate helps transmit nerve impulses in the brain. Theanine sometimes acts like glutamate in the body. But other times it seems to block the effects of glutamate. Theanine might also affect the brain chemicals GABA, dopamine, and serotonin.

People use L-theanine to improve mental function. It is also used for anxiety, mental impairment, stress, and other conditions, but there is no good scientific evidence to support these uses.

Don’t confuse theanine with another amino acid called threonine. These are not the same.

Uses & Effectiveness

Possibly Effective for

  • Memory and thinking skills (cognitive function). Taking L-theanine by mouth might help healthy people stay focused. It isn’t clear if adding L-theanine to caffeine works better than using either of those ingredients alone.

There is interest in using L-theanine for a number of other purposes, but there isn’t enough reliable information to say whether it might be helpful.

Side Effects

When taken by mouth: L-theanine is possibly safe when used short-term. Doses of up to 900 mg daily have been safely used for 8 weeks. It isn’t clear if L-theanine is safe to use for longer periods of time. It might cause mild side effects, such as headache or sleepiness."

" Interactions

Moderate Interaction

Be cautious with this combination

  • Medications for high blood pressure (Antihypertensive drugs) interacts with THEANINE

Theanine might lower blood pressure. Taking theanine along with medications that lower blood pressure might cause blood pressure to go too low. Monitor your blood pressure closely.

Minor Interaction

Be watchful with this combination

  • Sedative medications (CNS depressants) interacts with THEANINE

Some medications, called sedatives, can cause sleepiness and slowed breathing. There is some concern that theanine might also cause sleepiness and slowed breathing. But most research hasn’t shown this effect. For now, use theanine with caution if you are taking sedative medications.

Dosing

L-theanine is naturally found in tea and some mushrooms. As medicine, L-theanine has most often been used by adults in doses of 200-400 mg by mouth daily for 4-8 weeks. Speak with a healthcare provider to find out what dose might be best for a specific condition."

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122

I sometimes take L-theanine in the morning with my coffee because I do have high blood pressure and it helps to moderate the blood pressure raising effects of coffee. L-theanine is found naturally in tea and it’s especially high in matcha. After my first couple cups of coffee I often switch to green tea or even matcha (very strong japanese powdered green tea). Matcha is especially high in L-theanine. I’ve never had any problem with blood pressure going too low with L-theanine. I didn’t know that it increases vivid dreaming and I haven’t taken it at bedtime. I’ll have to try that. I don’t find that it gives me a “happy buzz” like kanna does.

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